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falciparum has becomecommon in Thailand, Cambodia and Myanmar,but is sporadic in Africa, South America andMiddleeast. Their efficacy is notreduced by organic matter and is enhanced inalkaline medium

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In general, the stimula-tion of afferent pathways back to the central nervoussystem results in release of neuropeptides such asopioids, serotonin, and the endocannabanoids (33).The end result is an influence on sympathetic andparasympathetic outflow to the heart and elsewhere,depending on the acupoint used.

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